- Given its particular design, the porous, curved, concave / convex surfaces of the particles accelerate the cellular reproduction of the elements that are deposited on them, facilitating neoformation and favoring the bone regeneration of the defect in which they have been grafted.
- Within a bone defect, the particles as a whole fulfill a scaffolding function with wide spaces of random shapes but with curved walls, which allow and facilitates the advancement of neoformation vessels between the particles, from the walls of the bone defect towards the center of the filling; This prevents the formation of necrotic centers with particles without vitality inside the graft, a problem that does occur with grafts of particles that remain very compact.
- Given their shape and porous surface, when the particles are deposited in a bone bed, they are locked together, allowing stable structures to be filled, gaining height 1 or 2 mm, which in many cases are essential for rehabilitation on titanium dental implants.
Revolutionary biomaterial with an innovative geometric design in the area of bone grafts, which improves the prognosis of bone regeneration, especially in large volume wounds. The particle that constitutes it, has a specific design and a particular manufacturing method, patented, for bone regeneration. It has been designed and generated by rapid prototyping, with 3D printing, a particle with a specific shape that, when inserted into a bone defect, together promotes cell regeneration and bone repair, into the graft and allows its growth in height.
The market is made up of three areas:
- Dental area: Maxillofacial and oral implantology
- Traumatology area: Spine traumatology and orthopedic surgery
- Veterinary area: Orthopedic surgery, especially horse and cattle (fine blood and breeders)
Early adopters have been identified among implant dentists and spine surgeons. The veterinary market has not been investigated, but it seems interesting, since it has no major regulations or restrictions for its clinical use.
- Testing on rats were performed (protocol preset in shell), with satisfactory results.
- The biomechanical properties of the particle were optimized
- Comparative studies are being done with other competing particles and with bone tissue from different areas of the body.
- In vitro tests is being initiated in large animals, in critical size defects, to demonstrate their behavior in large defects.
- The national market has been investigated, through the i-Corps methodology. Early adopters were identified.
- Bone cavity filling after exodontics
- Filling of bone cavities left by a cyst or a tumor removed from the jaw, elevation of the floor of the maxillary sinus, filling of a post-surgical defect in a long bone of a limb, etc.
- Increase in the height of an atrophied area of the jaw or any bone in the body (Note: A recipient bed that stabilizes the first layers of particles must be carved).
- Bone filling in lumbar fixation surgery (lumbar arthrodesis).
There is no ideal biomaterial for filling bone defects that meets all clinical-surgical requirements. Current biological grafts, derived from human or animal bone, lyophilized, present risks of infection and / or rejection. For their part, those of a synthetic nature tend to become infected and not integrate with the bone receptor bed. At best, if they are not complicated, they take several months to integrate into the surrounding bone.
- BRAIN-UC Contest – 2017
- Global Market UC Project – 2018
- Fundación Copec-UC Project – 2019